The 7th Annual Retreat for the COBRE Center

For Neuroplasticity at the University of Puerto Rico will be conducted using the GOOGLE MEET platform. We will begin at noon AST on May 21. The agenda will be sent via email shortly. We look forward to your participation. Thu May 21, 2020 12pm – 3pm

Details

We Are COBRE

Centers of Biomedical Research Excellence augment and strengthen institutional biomedical research capabilities by expanding and developing biomedical faculty research capability through support of a multidisciplinary center led by a peer-reviewed, NIH-funded investigator with expertise central to the theme of the grant proposal.

MENTORED PROJECTS

Demetrio Sierra,

PhD

Came to the UPR Medical Sciences Campus from the Massachusetts General Hospital / Harvard University in 2014.

Jose Colón,

PhD

Alpha-7 nAChR: Potential Therapeutic Target for Obesity Induced Cognitive Decline

Alfredo Ghezzi,

PhD

Epigenetic control of transcription dynamics in long-term alcohol neuroadaptation

Amaya Miquelajáuregui,

PhD

Role of microglial α7nAChR in diet induced brain inflammation.

Andrew Seeds,

PhD

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Pilots Projects

Stefanie Hampel,

PhD

Establishing an experimental model for probing the neural and molecular basis of abnormally repetitive behavior

Bianca Torres,

PhD

Polymorphism in neuroplasticity-related genes and its association with anxiety and depressive symptoms severity in Caribbean Hispanic patients

José E. Lizardi Ortiz

PhD

Role of Nicotinic Alpha 7 Autoreceptors in Striatal Cholinergic Interneurons

Steven Van Belleghem

PhD

Chromatin remodeling during butterfly brain development

Collaborative Seeds Projects

Dr. Nadezhda Sabeva

& Dr. Antonio H. Martins:

Ex vivo and in vivo models of Gulf War Illness Allow for Mechanistic Studies and the Search for Antidotes

Dra. Margarita Ortiz

& Dr. José Colón:

Synthesis of Biological Active Amino Derivatives and Multi-target Drugs for the Treatment of Alzheimer’s Disease

Dr. Priscila Sanabria

& Dr. Carlos Jiménez:

Xylazine effects on morphine-induced prefrontal cortex neuroplasticity

Dr. Yancy Ferrer

& Dr. Valance Washington:

Age-dependent involvement of inflammation associated receptors in hippocampal plasticity and neuroprotection after an ischemic insult

Dr. Luis Negrón

& Dr. José Rivera:

Lipid Dendrimer Nanoparticles for the Encapsulation of Brain-Derived Neurotrophic Factor and Simvastatin as a Non-Invasive Approach to Promote Neuroplasticity

Dr. Yancy Ferrer

& Dr. Antonio H. Martins:

Nuclear G-coupled Kinin-B2 Receptors in a Human hCMEC/D3 Blood Brain Barrier Cell title: Nuclear G-coupled B2 receptor

Request for Application or Funding Opportunities

PILOT PROJECT SUBMISSION

SEED PROJECT SUBMISSION

SUBPROJECT SUBMISSION

Research news

Institute faculty participate in Puerto Rico INBRE – COBRE Symposium

Faculty speakers from the Institute of Neurobiology presented their research at the Puerto Rico INBRE – COBRE Symposium, May 19-20, 2017.  Speakers in the Neurocience session included (left to right) Dr. Amaya Miquelajauregui, Dr. Kristin Branson (Keynote, Janelia Research Campus), Dr. Andrew Seeds, and Dr. Cristina Velåzquez.  Dr. Mark Miller served as session moderator.